Professor Stephen John Eglen | Faculty of Mathematics

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Career

1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
2000-2001 Lecturer, School of Informatics, Edinburgh
2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
2004-2006 Lecturer, DAMTP
2006-2015 Senior Lecturer, DAMTP
2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Compensatory redistribution of neuroligins and N‐cadherin following deletion of synaptic β1‐integrin

PW Keeley, B Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese

– J Comp Neurol

(2012)

520,

1349

(doi: 10.1002/cne.23027)

Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas

PW Keeley, BJ Sliff, SCS Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese

– The Journal of comparative neurology

(2012)

520,

1349

(doi: 10.1002/cne.23033)

Cellular Spacing: Analysis and Modelling of Retinal Mosaics

SJ Eglen

(2012)

365

(doi: 10.1007/978-94-007-3858-4_12)

Modeling developmental patterns of spontaneous activity

J Gjorgjieva, SJ Eglen

– Current Opinion in Neurobiology

(2011)

21,

679

(doi: 10.1016/j.conb.2011.05.015)

Analysis of simultaneous multielectrode recordings with 4,096 channels: changing dynamics of spontaneous activity in the developing retina

MH Hennig, A Maccione, M Gandolfo, M Down, SJ Eglen, L Berdondini, E Sernagor

– BMC neuroscience

(2011)

12,

p296

(doi: 10.1186/1471-2202-12-s1-p296)

Modeling developmental patterns of spontaneous activity.

J Gjorgjieva, SJ Eglen

– Current opinion in neurobiology

(2011)

21,

679

(doi: 10.1016/j.conb.2011.05.015)

Self-organization in the developing nervous system: theoretical models.

SJ Eglen, J Gjorgjieva

– HFSP journal

(2010)

3,

176

(doi: 10.2976/1.3079539)

Burst-Time-Dependent Plasticity Robustly Guides ON/OFF Segregation in the Lateral Geniculate Nucleus.

J Gjorgjieva, T Toyoizumi, SJ Eglen

– PLoS Computational Biology

(2009)

5,

e1000618

(doi: 10.1371/journal.pcbi.1000618)

A Multi-Component Model of the Developing Retinocollicular Pathway Incorporating Axonal and Synaptic Growth

KB Godfrey, SJ Eglen, NV Swindale

– Plos Computational Biology

(2009)

5,

e1000600

(doi: 10.1371/journal.pcbi.1000600)

Theoretical models of spontaneous activity generation and propagation in the developing retina.

KB Godfrey, SJ Eglen

– Mol Biosyst

(2009)

5,

1527

(doi: 10.1039/b907213f)