skip to content

Faculty of Mathematics


Nicholas Protonotarios

Research associate in applied mathematics

Dr. Nicholas E. Protonotarios is a research associate at the Department of Applied Mathematics and Theoretical Physics (DAMTP), University of Cambridge. His main research interests include the mathematics of medical imaging and mathematical image reconstruction in PET, SPECT and MRI.



Dikaios N, Protonotarios NE, Fokas AS, Kastis GA. Quantification of T1, T2 relaxation times from Magnetic Resonance Finger-printing radially undersampled data using analytical transformations. Magn Reson Imaging. 2021; 80:81–89. doi: 10.1016/j.mri.2021.04.013.

Protonotarios NE, Kastis GA, Dikaios N, Fokas AS. Piecewise Polynomial Inversion of the Radon Transform in Three Space Dimensions via Plane Integration and Applications in Positron Emission Tomography. Nonlinear Analysis, Differential Equations, and Applications. Springer Optimization and Its Applications, 2021; 173: 381-396. Springer, Cham. doi: 10.1007/978-3-030-72563-1_17.

Protonotarios NE, Charalambopoulos A, Kastis GA, Kacperski K, Fokas AS, A spline approach to parallel-hole collimator deblurring for aSRT-reconstructed SPECT images. IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE), 2019; 326–333. doi: 10.1109/BIBE.2019.00065.

Protonotarios NE, Kastis GA, Fokas AS. A new approach for the inversion of the attenuated Radon transform. Mathematical Analysis and Applications. Springer Optimization and Its Applications, 2019; 154: 433–457. Springer. doi: 10.1007/978-3-030-31339-5_16.

Protonotarios NE, Fokas AS, Kostarelos K, Kastis GA. The attenuated spline reconstruction technique for single photon emission computed tomography. J R Soc Interface. 2018; 15(148):20180509. doi: 10.1098/rsif.2018.0509.

Protonotarios NE, Fokas AS, Gaitanis A, Kastis GA. aSRT: A new analytic reconstruction algorithm for SPECT. IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD), 2016; 1–6. doi: 10.1109/NSSMIC.2016.8069451.

Protonotarios NE, Spyrou GM, Kastis GA. Automatic contour determination of multi-object nuclear medicine images. Comput Biol Med. 2017; 85:43–52. doi: 10.1016/j.compbiomed.2017.04.010.

Protonotarios NE, Spyrou GM, Kastis GA. Cumulative sums for edge determination of a single object in PET and SPECT images. 5th International Conference on Mathematical Modeling in Physical Sciences (IC-M2), 2016, J Phys: Conf Ser738(15):012010. doi: 10.1088/1742-6596/738/1/012010.